The NOBRL is located in the National Public Health Laboratories complex. The NPHL is located in Kenyatta National Hospital grounds off Ngong road, in Nairobi, Kenya. The laboratory was set up in November 2013 in order to address the rising burden of cancer and other non-communicable diseases.
The National Oncology Biochemistry Reference Laboratory provides specialized tests on referral basis relevant to non-communicable diseases (NCD’s) screening, diagnosis and surveillance to physicians, health care providers, and epidemiologists for the benefit of the patient and population.
NOBRL comprises three (3) sections
- Special chemistry:-where procedures are done on the Abbott Architect i1000SR platform. The Abbott Architect i1000SR high throughput machine is a two-step immunoassay which determines the presence/ quantities of certain biomolecules in human serum and plasma using Chemiluminescent Microparticle Immunoassay (CMIA)
- Biochemistry:- which utilizes Cobas C11 analyser to perform, renal function tests, liver function tests and lipid profile
- The HPV DNA testing: – Testing is done using HC2 technology which is a signal amplified hybridization antibody capture assay that utilizes microplate chemiluminescent detection.
All the sections within the NOBRL are located within one laboratory but on different benches each performing its specific functions.
The samples used for testing are:
- Blood (serum or plasma)
- Pap smear
- Tumor markers
National oncology reference laboratory provides testing for various cancer biomarkers (tumor markers) for different types of cancers such as ovarian, colorectal, prostate, breast, hepatocellular carcinoma and pancreatic cancers on the immunoassay platform.
- Thyroid function tests and reproductive hormones
NOBRL also provides testing for thyroid function and reproductive hormones such as FT3, FT4, TSH, LH, FSH, Estradiol, Progesterone and Testosterone etc.
- Diabetes diagnosis and monitoring
NOBRL provides diabetes diagnostic and monitoring tests such as random and fasting blood sugar and HBA1c.
NOBRL performs the following biochemical tests: Renal function tests, liver function tests and lipid profile using fully automated biochemistry analyzer
- Cancer screening and diagnosis
Cervical cancer screening – NOBRL provides testing for high risk HPV which is the leading cause of cervical cancer using the HPV DNA platform and pap smear .
The laboratory also performs fine needle aspirate for diagnosis of different types of cancers.
Hours of operation
Monday – Friday
Closed on Public holidays and Weekends
**We remain open when need arises
- The laboratory, in collaboration with stakeholders and financial support from EAPHLN project, developed “Integrated cancer screening and surveillance training curriculum for cervical, breast and prostate cancer” to be used to train healthcare workers in the country
- The unit also supported postgraduate students in research work whose findings will be shared with the Division once the data is analysed.
Role of the laboratory in the devolved system
The laboratory works closely with other laboratories in the counties which are pilot sites for the EAPHLN project by providing leadership on various aspects such as sample management.
- Acquire specialized equipment such as Human Papilloma Virus (HPV) molecular testing machine for cancer, haematology analyser, auto chemistry analyser and immunohistochemistry analyser
- The laboratory is targeting to be accredited in line with the ISO 15189
- Upgrade NOBRL test menu to include testing for drugs monitoring, vitamins, urinary iodine Surveys, immunology assays among others